The oldest active US 70 Business was born in 1960 as a replacement for US 70-A through Hillsborough and is the 1st US 70 Business. It runs on Revere Rd/Corbin St, then south along NC 86 Church St, then east out of town.

US 70-A #10 through Hillsborough 1949 Orange County

US 70 Business through Hillsborough 1962 Orange County

The 2nd US 70 Business was created 1960 as a renumbering of US 70-A through Durham. It initially used Hillsborough Rd, 9th St, Main St, Duke St, Chapel Hill St, Pettigrew St, Roxboro Rd (EB)/Magnum St (WB), Holloway Rd, and Miami Blvd.

US 70-A in Durham only 1958 Official

US 70-A becomes US 70 Business 1960 Official

In 1981, US 70 Bus was put on one-way splits with EB using Gregson and WB using Duke St between Main and Pettigrew.
Between 1985-87, US 70 Bus was rerouted to its current configuration using Morgan St WB and Main St/Downtown Loop/Ramseur St/Roxboro St EB.
Between 1991-93, US 70 Business was extended west over more US 70 to I-85 Exit 170.

US 70 Business rerouted in Durham 1981-82 Official

US 70 Business using Downtown Loop 1990-91 Official

US 70 Bus extended west of Durham 1993-94 Official

In Feb 2021 (thanks to dave Filpus), US 70 Bus was rerouted on its eastern end to follow NC 98 back to US 70 as part of the I-885 construction near the original east terminus.

The 5th US 70 Business was created in 1960 as a renumbering of US 70-A through Goldsboro. It uses Ash St, George St and Grantham St.

US 70-A through Goldsboro 1957 Wayne County

US 70 Business through Goldsboro 1962 Wayne County

The 7th US 70 Business was created about 1960 as a renumbering of mainline US 25-70 through Marshall. The eastern end was at today's NC 251.
In 1981, US 25-70 Business was extended east along what was now NC 251, then east replacing SR 1586 to the new US 25-70.
US 25-70 Business uses Jerry Allen Dr, Main St and Mashburn Hill Rd within Marshall.

US 25-70 through Marshall

US 25-70 Business in Marshall

US 25-70 business extended east to new US 25-70

The 8th US 70 Business was created about 1960 as what had been a few years prior mainline US 70 through Morganton. 1957 Burke County map showed route as non-primary.
Between 1969-72, US 70 Bus was split into one-way alignments. EB used Meeting St while WB used Union St.

US 70 Business in Morganton 1962 Burke County

US 70 Business spilts route 1982 Burke County

The 11th US 70 Business was created in 1991 or 1992 as a renumbering of mainline US 70 through Smithfield.
In June 2008 (NCDOT), US 70 Business was extended west over mainline 70 through Clayton to end at I-40 EXIT 306 near Garner.

US 70 through Smithfield 1972 Official

US 70 Business through Smithfield 1992-93 Official

US 70 Business through Clayton 2009 Official

The 12th US 70 Business was created July 1997 (NCDOT) as a renumbering of mainline US 70 through Selma. It is signed in the field as US 70 with no banner.

US 70 Business through Selma 1999 Official

Now a chronological look at 6 decommissioned US 70 Business routes:

The 3rd US 70 Business was was born in 1960 as a renumbering of US 70-A through Lexington. It used Main St through town, following the route of original NC 10.
In Sept 2003 (NCDOT), US 70 Bus was decommisioned. Part of Main St west of town is now part of NC 8.

US 70-A through Lexington 1952 Shell

US 70 Bus in Lexington 1962 Davidson County

The 4th US 70 Business was born 1960 as a renumbering of US 29-A through Thomasville. It used Main St and Turner Rd, following the route of original NC 10.
It appears US 70 Bus was decommissioned by 1962.

The 6th US 70 Business was created in 1960 as a renumbering of US 70-A through Kinston. It used W. Vernon Ave and S. Queen St through town. It was 100% duplexed with US 258 Business. US 70 Bus was removed in March 2023 (NCDOT). Vernon Ave became SR 1295, while Queen St remains NC 58.

US 70-A through Kinston 1957 Lenoir County

US 70 Business through Kinston 1962 Lenoir County

The 9th US 70 Business was created about 1978 as a renumbering of mainline US 70 through New Bern. It began at Milburnie Rd and used Neuse Blvd, Broad St and E. Front St across the Trent River.
In 1979, US 70 Bus was extended over Milburnie Rd (which had briefly been mainline 70) south to the US 70 freeway.
In May 2000 (NCDOT), US 70 Bus was removed from Neuse Blvd (remained NC 55) and instead replaced US 17 southwest to the US 70 freeway.
In 2010, US 70 Business was decommissioned. A bit of Broad St remains part of NC 55 but the rest is currently unnumbered.

US 70 bypasses New Bern 1978-79 Official

US 70 Bus moved to Milburnie 1979-80 Official

US 70 Bus replaces US 17 2002 Official

The 10th US 70 Business was created Nov 1979 (NCDOT) as a renumbering of mainline US 70 on Wilmington St and part of the Raleigh Beltline.
US 70 Business was removed from the beltline and restored to mainline US 70 on the Wilmington St portion in July 1991 (NCDOT).

US 70 onto Beltline 1984-85 Official

US 70 Business on Wilmington St and a little Beltline 1990-91 Official

US 70 Business removed 1992 Official

The 13th US 70 Business was created in 2018 after US 70 was given a new bridge between Morehead City and Beaufort which also created a full bypass of Beaufort. US 70 Business was assigned to former US 70 on Live Oak St and Cedar Ave west to Turner St, then north on Turner St which was constructed to extend out to the US 70 Bypass.
By Oct 2019 (per Vespertine), US 70 Business was deposted. An e-mail to NCDOT confirmed that this route existed but was downgraded to secondary status so that the streets can be turned over to the City of Beaufort.