US 601
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From: near Pineland (Jasper County)
To: North Carolina State Line above Pageland (Chesterfield County)
Total Length: 181.4 miles  
Nationally, US 601 runs from Pineland to US 52 Mt. Airy NC.
ROUTE LOG
US 321: 0 - 0
SC 462: 3.7 - 3.7
Hampton-Jasper Line: 2.2 - 5.9
SC 333: 3.2 - 9.1
SC 3: 4.8 - 13.9
US 278 EB, SC 363 EB: 9.2 - 23.1
US 278 WB, SC 363 WB: 0.5 - 23.6
Colleton-Jasper Line: 9.8 - 33.4
SC 641: 2.9 - 36.3
Bamberg-Colleton Line: 1.8 - 38.1
SC 64: 3.3 - 41.4
US 301 SB: 13.4 - 54.8
US 78: 0.9 - 55.7
Orangeburg-Bamberg Line: 3.1 - 58.8
SC 332: 2.6 - 61.4
SC 70: 6.4 - 67.8
SC 4: 3.3 - 71.1
SC 33: 1.8 - 72.9
US 178 Bus: 0.6 - 73.5
US 21 Bus SB, US 301 NB: 0.6 - 74.1
SC 33: 0.1 - 74.2
US 21, US 21 Bus END, US 178: 1.0 - 75.2
I-26 (exit 145): 4.1 - 79.3
Calhoun-Orangeburg Line: 3.1 - 82.4
US 176: 3.2 - 85.6
SC 6: 1.8 - 87.4
SC 419: 7.6 - 95.0
SC 267: 1.4 - 96.4
Richland-Calhoun Line: 2.0 - 98.4
SC 48: 4.1 - 102.5
SC 764: 4.3 - 106.8
SC 263: 2.9 - 109.7
US 76, US 378: 2.7 - 112.4
SC 262: 4.9 - 117.3
Kershaw-Richland Line: 5.0 - 122.3
I-20 (exit 92), SC 12: 7.8 - 130.1
US 1 SB: 2.1 - 132.2
SC 34 WB: 0.3 - 132.5
US 1 NB, US 521 SB, SC 34 EB: 4.0 - 136.5
SC 97: 2.0 - 138.5
Lancaster-Kershaw Line: 15.3 - 153.8
US 521 NB, US 521 Bus BEGIN: 3.1 - 156.9
SC 157: 0.3 - 157.2
US 521 Bus NB: 0.2 - 157.4
SC 265: 5.6 - 163.0
SC 903 WB: 1.7 - 164.7
SC 903 EB: 0.1 - 164.8
Chesterfield-Lancaster Line: 5.3 - 170.1
SC 9 WB: 4.6 - 174.7
SC 207: 2.8 - 177.5
SC 9 EB, SC 151 Bus: 0.5 - 178.0
SC 151: 1.1 - 179.1
NC STATE LINE: 2.3 - 181.4
 Creation: Appeared in late 1926 as an original US Highway as an addition to SC 41 from US 17-76 Florence to end at US 1 (now S-13-148 Cash Rd) Cheraw.
Adjustments: In 1928, SC 41 was removed from US 601.
In 1931, US 601 was removed from S-13-494 Macedonia Church Rd and Juniper road south of Cheraw and placed on modern US 52 to modern US 1.
In 1932 (bridge date), US 601 was removed from Creek Crossing Dr and Pine Log Cir (no longer crosses Black Creek) belwo Dovesville.
In 1933, US 601 was extended replacing SC 96 into North Carolina.
In 1935, US 601 was renumbered as US 52, removing US 601 from South Carolina altogether.

1927 Clasons
US 601 added to SC 41 Florence to Cheraw
1927 Clasons
1933 Official
US 601 extended to North Carolina
1933 Official
1935 Official
US 601 replaced by US 52
1935 Official

In 1951, US 601 was rerouted in North Carolina and then extended back into South Carolina, replacing SC 151 to Pageland; following SC 9 west a little; replacing SC 902 and SC 265 to Kershaw; added to US 521 and US 1 to Camden and Lugoff; replacing SC 26 to Orangeburg; added to US 301 to Bamberg; replaced SC 36 to US 321 near Pineland; followed US 321 to end at US 17 Hardeeville.

1949 Official
state routes Kershaw to Pageland
1949 Official
1951 Official
US 601 from Kershaw to Pageland
1951 Official
1950 Official
SC 26 Lugoff to Orangeburg
1950 Official
1951 Official
SC 26 replaced by US 601
1951 Official

In 1954, US 601 was rerouted in Orangeburg to its current routing by staying on Magnolia a little further. Russell St became an extended SC 33.

1951 Official
US 601 via Russell St
1951 Official
1966 Official
US 601 rerouted
1966 Official

In 1965 (bridge date), US 601 was removed from Wintertide Dr and S-13-823 in the Lynches River area. The 1922 bridge over the river is still accessible.

1963 Lancaster County
US 601 original Lynches River approach
1963 Lancaster County
1967 Lancaster County
US 601 straightened out
1967 Lancaster County

About 1974, US 601 was extended south to I-95 as a multiplex with US 17.
In 1976, US 601 south was truncated to its current US 321 endpoint leaving behind US 321 and US 17.

1950 Official
SC 36 south of Bamberg
1950 Official
1951 Official
US 601 Bamberg to Hardeeville
1951 Official
1976 Official
US 601 truncated to US 321
1976 Official

Sometime after 1991, US 601 appears to have been placed on US 521's bypass of Kershaw, then used S-29-62 Hilton St to get back to US 601's orginal route. Main St became a posted US 601 Business. Note that SCDOT maps do not show this despite it being heavily posted this way.
Improvements: Paved only from Florence to Darlington in 1928, then to Society Hill in 1932; fully paved to Cheraw in 1934. When US 601 returned to S.C. it was fully paved everywhere.
The first multilane section of US 601 appeared 1962, from SC 4 to SC 33.
The next sections to be upgraded between 1968-69 was from Camden to I-20
In 1970, US 601 was multilaned SC 4 to SC 70.
In 1973, US 601 was 4-laned from Orangeburg to I-26 and from SC 70 to the US 301 SB split.
In 1974, US 601 was 4-laned from Camden to SC 97.
In 2007 or 2008, US 601 was multilaned from I-26 to the Calhoun County line.
In 2013, US 601 was multilaned from Orangeburg-Calhoun line to US 176.
Comment: US 601 is little changed from its reintroduction to the Palmetto State.
There is a posted US 601 TRUCK for Camden that uses S-28-130 Springdale Dr/Boykin Rd and serves as a natural bypass for Camden.

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Page last modified 2 September 2017